Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.45 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12959534 | 0.97 | RARA (0.44) | RARARARBHTR1AHTR2ADRD3 | |
| SCHEMBL12633864 | 0.85 | RARA (0.45) | RARARARBHTR1AHTR2ADRD3 | |
| SCHEMBL2017424 | 0.83 | RARB (0.52) | RARARARBHTR1AHTR2ADRD3 | |
| SCHEMBL2011986 | 0.83 | RARA (0.47) | RARARARBHTR1AHTR2ADRD3 | |
| SCHEMBL12806013 | 0.82 | MAPT (0.47) | RARARARBRARG | |
| SCHEMBL12633657 | 0.82 | RARB (0.43) | RARARARBHTR1AHTR2ADRD3 | |
| SCHEMBL2016847 | 0.82 | RARA (0.51) | RARARARBHTR1AHTR2ADRD3 | |
| SCHEMBL2014838 | 0.82 | RARA (0.46) | RARARARBHTR1AHTR2ADRD3 | |
| SCHEMBL2017413 | 0.81 | RARB (0.54) | RARARARBHTR1AHTR2ADRD3 | |
| SCHEMBL31060378 | 0.81 | RARB (0.47) | RARARARBHTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072791-A1 | SPHINGOSINE KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2011-06-23 | — | — | WO | disclosed |