Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 6/20 | 0.39 |
| ▸ | BTK | Q06187 | 6/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040780 | 0.86 | ABCG2 (0.45) | F10ABCG2MAPTLMNAPKM | |
| SCHEMBL4203388 | 0.70 | TSHR (0.67) | ABCG2MAPTLMNAMEN1KMT2A | |
| SCHEMBL16280446 | 0.70 | JAK2 (0.43) | F10ABCG2MAPTLMNAPKM | |
| SCHEMBL16280573 | 0.70 | MAPT (0.41) | F10ABCG2MAPTLMNAPKM | |
| SCHEMBL20500742 | 0.70 | PIN1 (0.42) | JAK3BTKPIN1 | |
| SCHEMBL12371228 | 0.69 | ABCG2 (0.44) | F10ABCG2MAPTLMNAMEN1 | |
| SCHEMBL30043252 | 0.69 | TSHR (0.64) | ABCG2MAPTLMNAMEN1KMT2A | |
| SCHEMBL6273333 | 0.69 | TSHR (0.64) | ABCG2MAPTLMNAMEN1KMT2A | |
| SCHEMBL7997068 | 0.68 | MAPT (0.73) | MAPTLMNAMEN1KMT2ACYP2C9 | |
| SCHEMBL30098452 | 0.68 | MAPT (0.73) | MAPTLMNAMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079231-A1 | COMPOUNDS THAT MODULATE EGFR ACTIVITY AND METHODS FOR TREATING OR PREVENTING CONDITIONS THEREWITH | GATEKEEPER PHARMACEUTICAL, INC. (US) | 2011-06-30 | — | — | WO | disclosed |