Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635555 | 0.84 | KMT2A (0.65) | SLC7A5KMT2ATRPA1MAPTALDH1A1 | |
| SCHEMBL12636160 | 0.83 | KMT2A (0.63) | KMT2AMAPTALDH1A1POLB | |
| SCHEMBL12635554 | 0.81 | KMT2A (0.50) | SLC7A5KMT2ATRPA1MAPTALDH1A1 | |
| SCHEMBL12301533 | 0.79 | SLC7A5 (0.65) | SLC7A5 | |
| SCHEMBL9337506 | 0.76 | GSK3B (0.53) | SLC7A5KMT2ATRPA1MAPTGSK3B | |
| SCHEMBL5382573 | 0.76 | SLC7A5 (0.60) | SLC7A5ALDH1A1 | |
| SCHEMBL7384982 | 0.75 | SLC7A5 (0.63) | SLC7A5MAPTALDH1A1 | |
| SCHEMBL3499880 | 0.75 | SLC7A5 (0.63) | SLC7A5MAPT | |
| SCHEMBL8871718 | 0.75 | MAPT (0.53) | KMT2ATRPA1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL29451629 | 0.74 | SLC7A5 (0.50) | SLC7A5KMT2ATRPA1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |