SCHEMBL126362

SCHEMBL126362

CCCCCCCCCCCCCCCCCCC(CO)N(CCO)CCO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
CYP2D6 P10635 2/20 0.41
SPHK1 Q9NYA1 2/20 0.41
GMNN O75496 1/20 0.41
POLB P06746 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41
BLM P54132 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
CETP P11597 1/20 0.41
HTT P42858 1/20 0.41
UBE2N P61088 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11481045 1.00 LMNA (0.48) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL27478764 1.00 LMNA (0.48) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL31532959 1.00 LMNA (0.48) LMNACYP2D6SPHK1GMNNPOLB
Hydrochloric Acid SCHEMBL3903416 0.98 LMNA (0.47) LMNACYP2D6SPHK1GMNNPOLB
Ammonia Solution, Strong SCHEMBL6141913 0.98 LMNA (0.47) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL28191238 0.98 LMNA (0.45) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL7717013 0.96 LMNA (0.45) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL28355331 0.96 LMNA (0.45) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL1243043 0.96 LMNA (0.45) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL28359323 0.96 LMNA (0.45) LMNACYP2D6SPHK1GMNNPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3625 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10945960-B2 Celecoxib and amlodipine formulation and method of making the same DEXCEL LTD. (IL) 2021-03-16 US claimed
US-10925835-B2 Celecoxib and amlodipine formulation and method of making the same DEXCEL LTD. (IL) 2021-02-23 US claimed
US-20200390713-A1 CELECOXIB AND AMLODIPINE FORMULATION AND METHOD OF MAKING THE SAME PURPLE BIOTECH LTD (IL) 2020-12-17 US claimed
CN-111065382-A Formula of celecoxib and amlodipine and preparation method thereof 德西尔公司 2020-04-24 CN claimed
US-20200093128-A1 ACIDULATED SURFACTANT COMPOSITIONS AND METHODS OF REDUCING MICROBIAL LOAD THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2020-03-26 US claimed
US-20190282507-A1 CELECOXIB AND AMLODIPINE FORMULATION AND METHOD OF MAKING THE SAME PURPLE BIOTECH LTD (IL) 2019-09-19 US claimed
US-20190008777-A1 CELECOXIB AND AMLODIPINE FORMULATION AND METHOD OF MAKING THE SAME PURPLE BIOTECH LTD (IL) 2019-01-10 US claimed
WO-2019008583-A1 CELECOXIB AND AMLODIPINE FORMULATION AND METHOD OF MAKING THE SAME DEXCEL LTD. (IL) 2019-01-10 WO claimed
US-20110166225-A1 ORAL LIQUID COMPOSITIONS OF RHEIN OR DIACEREIN VERMA HIMANSHU 2011-07-07 US claimed
EP-2280697-A1 ORAL LIQUID COMPOSITIONS OF RHEIN OR DIACEREIN Wockhardt Research Centre (IN) 2011-02-09 EP claimed
WO-2009133430-A1 TOPICAL COMPOSITIONS OF RHEIN OR DIACEREIN WOCKHARDT RESEARCH CENTRE (IN) 2009-11-05 WO claimed
WO-2009133431-A1 ORAL LIQUID COMPOSITIONS OF RHEIN OR DIACEREIN WOCKHARDT RESEARCH CENTRE (IN) 2009-11-05 WO claimed
US-20260146047-A1 MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-28 US disclosed
US-20260147006-A1 SCREENING METHOD TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-28 US disclosed
US-12637418-B2 Heterocyclic compounds as antagonist of NMDA TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-26 US disclosed
CN-122094696-A Adiponectin enhancer, oral composition for adiponectin enhancement, and use of plasmalogen 2026-05-26 CN disclosed
EP-0608870-A1 Quinoline or quinazoline derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-08-03 EP disclosed
EP-0579221-A1 Cephem compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-01-19 EP disclosed
EP-0567107-A1 Quinoline and quinazoline derivatives for treating arthritis TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-27 EP disclosed
EP-0562599-A1 Condensed thiadiazole derivative, method of its production, and use thereof Takeda Chemical Industries, Ltd. (JP) 1993-09-29 EP disclosed