Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PNP | P00491 | 7/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12636642 | 0.94 | MEN1 (0.49) | CNR2CNR1MEN1KMT2AHBB | |
| SCHEMBL12636652 | 0.86 | MEN1 (0.49) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12636629 | 0.86 | MEN1 (0.54) | MEN1KMT2AHBBMAPK1F2 | |
| SCHEMBL12636647 | 0.85 | MEN1 (0.52) | CNR1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL1880253 | 0.85 | MEN1 (0.52) | CNR1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL12636648 | 0.85 | MEN1 (0.52) | CNR1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL12636693 | 0.84 | MEN1 (0.61) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12636635 | 0.81 | MEN1 (0.54) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12671790 | 0.81 | MEN1 (0.60) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL1898365 | 0.81 | MEN1 (0.45) | CNR1MEN1KMT2AHBBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-05-05 | — | — | US | disclosed |
| US-20110105417-A1 | Drug Conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | ABCB1, SLCO2B1, ABCG2 | CNR2 1702/4885CNR1 1239/4885MEN1 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.