Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HBB | P68871 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PNP | P00491 | 7/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.47 |
| ▸ | POLG | P54098 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12671790 | 0.92 | MEN1 (0.60) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12636643 | 0.92 | MEN1 (0.61) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12636693 | 0.90 | MEN1 (0.61) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12636652 | 0.88 | MEN1 (0.49) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12671989 | 0.87 | MEN1 (0.66) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL9019935 | 0.84 | MEN1 (0.68) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12671791 | 0.84 | MEN1 (0.54) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12636665 | 0.82 | BLM (0.45) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12636636 | 0.81 | CNR2 (0.49) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL9583513 | 0.81 | PDE3A (0.57) | MEN1KMT2AHBBMAPK1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-05-05 | — | — | US | disclosed |
| US-20110105417-A1 | Drug Conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | ABCB1, SLCO2B1, ABCG2 | MEN1 1850/4885KMT2A 3940/4885HBB 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.