Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10703049 | 0.88 | TMEM97 (0.37) | GRM2TMEM97SIGMAR1POLBLMNA | |
| SCHEMBL8539003 | 0.88 | TMEM97 (0.37) | GRM2TMEM97SIGMAR1POLBLMNA | |
| SCHEMBL13013398 | 0.88 | TMEM97 (0.37) | GRM2TMEM97SIGMAR1POLBLMNA | |
| SCHEMBL22360663 | 0.87 | TMEM97 (0.38) | GRM2TMEM97SIGMAR1TP53OPRM1 | |
| SCHEMBL17068337 | 0.84 | TMEM97 (0.36) | GRM2TMEM97SIGMAR1POLBLMNA | |
| SCHEMBL17068318 | 0.84 | TMEM97 (0.36) | GRM2TMEM97SIGMAR1POLBLMNA | |
| SCHEMBL16950203 | 0.81 | HDAC3 (0.33) | GRM2TMEM97SIGMAR1TP53OPRM1 | |
| SCHEMBL16950206 | 0.81 | HDAC3 (0.33) | GRM2TMEM97SIGMAR1TP53OPRM1 | |
| SCHEMBL6851717 | 0.81 | TMEM97 (0.38) | GRM2TMEM97SIGMAR1TP53OPRM1 | |
| SCHEMBL886854 | 0.81 | TMEM97 (0.38) | GRM2TMEM97SIGMAR1TP53OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-05-05 | — | — | US | disclosed |
| US-20100322880-A1 | UVA FILTERS BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | ABCB1, SLCO2B1, ABCG2 | GRM2 1479/4885TMEM97 217/4885SIGMAR1 544/4885 |
| US-20100322880-A1 | UVA FILTERS BASED ON ASCORBIC ACID DERIVATIVES | C1R, VDR, C1S | GRM2 4485/4885TMEM97 4829/4885SIGMAR1 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.