SCHEMBL1264031

SCHEMBL1264031

CCCCCC(C)(C)c1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 17/20 0.42
CNR2 P34972 16/20 0.42
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28523920 0.87 NPC1 (0.42) CNR1CNR2NPC1LMNARAB9A
SCHEMBL123853 0.87 NPC1 (0.51) CNR1CNR2NPC1LMNARAB9A
SCHEMBL5834500 0.87 CNR2 (0.42) CNR1CNR2NPC1LMNARAB9A
SCHEMBL769340 0.87 CNR2 (0.42) CNR1CNR2NPC1LMNARAB9A
SCHEMBL2464346 0.86 CNR1 (0.52) CNR1CNR2NPC1LMNARAB9A
SCHEMBL8861278 0.85 CNR1 (0.39) CNR1CNR2NPC1RAB9A
SCHEMBL8741026 0.84 CNR1 (0.38) CNR1CNR2NPC1RAB9A
SCHEMBL10670861 0.84 CNR1 (0.43) CNR1CNR2NPC1LMNARAB9A
SCHEMBL1264030 0.84 CYP3A4 (0.50) NPC1LMNARAB9A
SCHEMBL30157198 0.84 CYP3A4 (0.50) NPC1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US claimed
US-5112890-A Piperidine compound with oxygen bonded to ring nitrogen CIBA-GEIGY CORPORATION (US) 1992-05-12 US claimed
US-5064883-A Stabilization of acid catalyzed thermoset resins with n-hydroxy hindered amines CIBA-GEIGY CORPORATION (US) 1991-11-12 US claimed
US-5006577-A Durable, weatherproof CIBA-GEIGY CORPORATION (US) 1991-04-09 US claimed
US-4426471-A TETRAALKYLPIPERIDINES CIBA-GEIGY CORPORATION (US) 1984-01-17 US claimed
US-4089839-A STABILIZERS/AGENTS UNIROYAL, INC. (US) 1978-05-16 US claimed
US-3978074-A CATALYTIC HYDROGENATION UNIROYAL INC. (US) 1976-08-31 US claimed
CN-115644556-A Cushioning element utilizing foam particles 耐克创新有限合伙公司 2023-01-31 CN disclosed
CN-115644557-A Cushioning element utilizing foam particles 耐克创新有限合伙公司 2023-01-31 CN disclosed
US-8163934-B2 Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole CHANG CHIA-HU (US) 2012-04-24 US disclosed
EP-2332013-A1 ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE Chang, Chia-Hu (US) 2011-06-15 EP disclosed
US-20110038816-A1 Ultraviolet light absorbing ketones of 2-(2-hydroxyhenyl) benzotriazole CHANG CHIA-HU 2011-02-17 US disclosed
US-7847103-B2 Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole CHANG CHIA-HU 2010-12-07 US disclosed
WO-2002012202-A2 PROCESSES FOR THE PREPARATION OF BENZOTRIAZOLE UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) 2002-02-14 WO disclosed
EP-1144391-A1 ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES Ciba SC Holding AG (CH) 2001-10-17 EP disclosed
WO-2000043376-A1 ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-07-27 WO disclosed
US-6040455-A REACTING A HALOBENZOTRIAZOLE COMPOUND WITH ALIPHATIC, PHENYLALKYL OR ARYL MERCAPTAN COMPOUND TO FORM 5-THIO SUBSTITUTED BENZOTRIAZOLE, OXIDIZING WITH HYDROGEN PEROXIDE TO FOR 5-SULFONE SUBSTITUED BENZOTRIAZOLE COMPOUND CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-03-21 US disclosed
US-4089839-A STABILIZERS/AGENTS UNIROYAL, INC. (US) 1978-05-16 US disclosed
US-4089839-A STABILIZERS/AGENTS UNIROYAL, INC. (US) 1978-05-16 US disclosed
US-3978074-A CATALYTIC HYDROGENATION UNIROYAL INC. (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110038816-A1 Ultraviolet light absorbing ketones of 2-(2-hydroxyhenyl) benzotriazole HCRTR2, HCRTR1, POLL CNR1 254/4885CNR2 104/4885NPC1 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.