Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | Q9HBH1 | 1/20 | 0.35 | |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995173 | 0.87 | ALDH1A1 (0.42) | PLA2G2CALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL12640380 | 0.86 | ALDH1A1 (0.37) | PLA2G2CALDH1A1LMNAKISS1RCA1 | |
| SCHEMBL13995175 | 0.81 | USP2 (0.34) | PLA2G2CALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL13995176 | 0.80 | ALDH1A1 (0.37) | PLA2G2CALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL13995181 | 0.80 | TDP1 (0.36) | PLA2G2CALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL12228505 | 0.78 | PLA2G2C (0.47) | PLA2G2CALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL12360353 | 0.75 | MAPT (0.46) | PLA2G2CALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL14471116 | 0.75 | HDAC7 (0.45) | PLA2G2CALDH1A1USP2CYP3A4MAPT | |
| SCHEMBL13995178 | 0.75 | MAPT (0.43) | PLA2G2CALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL13995179 | 0.75 | MAPT (0.43) | PLA2G2CALDH1A1LMNAUSP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935782-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090306335-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | NATIONAL SCIENCE FOUNDATION | 2009-12-10 | — | — | US | disclosed |