Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14408875 | 0.85 | KMT2A (0.58) | KMT2AALDH1A1SLC1A2MMEMEN1 | |
| SCHEMBL12310879 | 0.85 | KMT2A (0.58) | KMT2AALDH1A1SLC1A2MMEMEN1 | |
| SCHEMBL7523650 | 0.83 | KMT2A (0.61) | KMT2AALDH1A1SLC1A2MMEMEN1 | |
| SCHEMBL7523647 | 0.83 | KMT2A (0.61) | KMT2AALDH1A1SLC1A2MMEMEN1 | |
| SCHEMBL27998598 | 0.80 | ALDH1A1 (0.56) | KMT2AALDH1A1SLC1A2MEN1MAPT | |
| SCHEMBL10432369 | 0.80 | KMT2A (0.59) | KMT2AALDH1A1SLC1A2MMEMEN1 | |
| SCHEMBL12251345 | 0.80 | KMT2A (0.63) | KMT2AALDH1A1SLC1A2MMEMEN1 | |
| SCHEMBL15338749 | 0.80 | KMT2A (0.63) | KMT2AALDH1A1SLC1A2MMEMEN1 | |
| SCHEMBL8760 | 0.79 | KMT2A (0.67) | KMT2AALDH1A1SLC1A2MMEMEN1 | |
| SCHEMBL24050017 | 0.79 | BACE1 (0.59) | KMT2AALDH1A1SLC1A2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964646-B2 | 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2011-06-21 | — | — | US | disclosed |