SCHEMBL12640588

SCHEMBL12640588

CN(C)CCCNC(=O)c1cccc(C2=C3C(=O)NC(c4ccc(Br)cc4)=C3C(=O)N2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FYN P06241 2/20 0.49
METAP2 P50579 1/20 0.49
PDE1A P54750 1/20 0.47
PDE1B Q01064 1/20 0.47
PDE4D Q08499 1/20 0.47
PDE7A Q13946 1/20 0.47
PDE1C Q14123 1/20 0.47
PDE3A Q14432 1/20 0.47
TMEM97 Q5BJF2 2/20 0.46
SIGMAR1 Q99720 2/20 0.46
MAPK8 P45983 2/20 0.46
CHUK O15111 1/20 0.46
INSR P06213 1/20 0.46
CAMKK2 Q96RR4 1/20 0.46
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12640625 0.93 FYN (0.53) FYNMETAP2PDE1APDE1BPDE4D
SCHEMBL12577540 0.92 METAP2 (0.52) FYNMETAP2PDE1APDE1BPDE4D
SCHEMBL12640626 0.92 MEN1 (0.53) FYNMETAP2PDE1APDE1BPDE4D
SCHEMBL12640733 0.90 PDE1A (0.51) FYNMETAP2PDE1APDE1BPDE4D
SCHEMBL21609758 0.80 MAPK1 (0.48) METAP2PDE1APDE1BPDE4DPDE7A
SCHEMBL30038995 0.80 MAPK1 (0.48) METAP2PDE1APDE1BPDE4DPDE7A
SCHEMBL12577520 0.80 SMN1; SMN2 (0.59) L3MBTL1
SCHEMBL12640646 0.80 HPGD (0.52) PDE1APDE1BPDE4DPDE7APDE1C
SCHEMBL12577672 0.79 HPGD (0.57) FYNPDE1APDE1BPDE4DPDE7A
SCHEMBL14085082 0.79 SMN1; SMN2 (0.57) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2303967-B1 IMPROVED, RED COLOUR FILTER COMPOSITION BASF SE (DE) 2013-11-13 EP disclosed
US-8273269-B2 Red colour filter composition BASF SE (DE) 2012-09-25 US disclosed
US-20110155973-A1 IMPROVED, RED COLOUR FILTER COMPOSITION BASF SE (DE) 2011-06-30 US disclosed
WO-2009144115-A1 IMPROVED, RED COLOUR FILTER COMPOSITION BASF SE (DE) 2009-12-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110155973-A1 IMPROVED, RED COLOUR FILTER COMPOSITION NR2E3, MRPS22, NR2C2 FYN 2966/4885METAP2 1710/4885PDE1A 4763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.