Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876156 | 0.79 | EPHX2 (0.81) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 | |
| SCHEMBL13702303 | 0.78 | L3MBTL1 (0.65) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 | |
| SCHEMBL4189504 | 0.77 | EPHX2 (0.82) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 | |
| SCHEMBL13702153 | 0.75 | L3MBTL1 (0.65) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 | |
| SCHEMBL4178518 | 0.75 | EPHX2 (0.73) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 | |
| SCHEMBL15350981 | 0.74 | EPHX2 (0.55) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 | |
| SCHEMBL31498883 | 0.73 | L3MBTL1 (0.65) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 | |
| SCHEMBL15351096 | 0.73 | EPHX2 (0.59) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 | |
| SCHEMBL27931725 | 0.73 | L3MBTL1 (0.54) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 | |
| SCHEMBL13702416 | 0.73 | L3MBTL1 (0.68) | EPHX2CYP2C9CYP2C19CYP2J2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076678-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-30 | — | — | WO | disclosed |