SCHEMBL12640693

SCHEMBL12640693

Fc1ccc(/C2=N/c3ccccc3/C(c3ccc(F)cc3)=N\c3ccccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.50
MAPT P10636 5/20 0.41
GAA P10253 3/20 0.41
LMNA P02545 3/20 0.41
CNR1 P21554 1/20 0.40
PTGS2 P35354 2/20 0.39
PTGS1 P23219 1/20 0.39
KDM4E B2RXH2 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
POLB P06746 2/20 0.39
RECQL P46063 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
MAPK14 Q16539 1/20 0.39
GSK3A P49840 2/20 0.38
GSK3B P49841 2/20 0.38
FLT3 P36888 1/20 0.38
CCNB2 O95067 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13583465 1.00 IDO1 (0.50) IDO1MAPTGAALMNACNR1
SCHEMBL14455172 0.92 IDO1 (0.46) IDO1MAPTGAALMNACNR1
SCHEMBL28425832 0.85 ALDH1A1 (0.54) IDO1MAPTLMNAPTGS2PTGS1
SCHEMBL17321749 0.83 IDO1 (0.64) IDO1MAPTGAALMNAKDM4E
SCHEMBL17321751 0.83 IDO1 (0.64) IDO1MAPTGAALMNAKDM4E
SCHEMBL18977949 0.82 IDO1 (0.69) IDO1MAPTGAALMNAKDM4E
SCHEMBL14455170 0.79 MAPT (0.56) IDO1MAPTGAALMNAKDM4E
SCHEMBL12912867 0.79 IDO1 (0.50) IDO1MAPTGAALMNAKDM4E
SCHEMBL14455176 0.79 IDO1 (0.50) IDO1MAPTGAALMNACNR1
SCHEMBL17321599 0.78 MAPT (0.55) IDO1MAPTGAALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2242789-B1 COPOLYMERS OF DIBENZODIAZOCINE WITH DIFUNCTIONAL MONOMERS CONTAINING SULFONE AND/OR KETONE UNITS SOLVAY SPECIALTY POLYMERS USA (US) 2017-05-24 EP disclosed
US-20120283407-A1 New polyamide, polyimide or polyamide-imide comprising dibenzodiazocine units SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2012-11-08 US disclosed
US-20120283407-A1 New polyamide, polyimide or polyamide-imide comprising dibenzodiazocine units SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2012-11-08 US disclosed
US-20120283407-A1 New polyamide, polyimide or polyamide-imide comprising dibenzodiazocine units SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2012-11-08 US disclosed
WO-2011076674-A1 NEW POLYAMIDE, POLYIMIDE OR POLYAMIDE-IMIDE COMPRISING DIBENZODIAZOCINE UNITS SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-06-30 WO disclosed
US-7238771-B2 Dibenzodiazocine polymers SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-07-03 US disclosed
US-7238771-B2 Dibenzodiazocine polymers SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-07-03 US disclosed