SCHEMBL1264103

SCHEMBL1264103

c1ccc(C2CCC3OC3C2)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.48
AKR1C1 Q04828 1/20 0.48
SLC18A3 Q16572 2/20 0.42
SIGMAR1 Q99720 1/20 0.42
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 2/20 0.40
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
GRIN2B Q13224 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11788523 0.89 SLC18A3 (0.52) AKR1C3AKR1C1SLC18A3SIGMAR1CYP2D6
SCHEMBL23082747 0.87 MEN1 (0.43) AKR1C3AKR1C1SLC18A3SIGMAR1CYP2D6
SCHEMBL11789430 0.87 MEN1 (0.43) AKR1C3AKR1C1SLC18A3SIGMAR1CYP2D6
SCHEMBL8529959 0.82 AKR1C3 (0.32) AKR1C3AKR1C1
Methyl Alcohol SCHEMBL8601845 0.81 SLC18A3 (0.42) AKR1C3AKR1C1SLC18A3SIGMAR1KMT2A
SCHEMBL11789570 0.80 HTR3A (0.43) SLC18A3KMT2ALMNAHPGDMEN1
SCHEMBL10895189 0.79 AKR1C3 (0.61) AKR1C3AKR1C1SLC18A3SIGMAR1CYP2D6
SCHEMBL190417 0.74 SLC18A3 (0.67) AKR1C3AKR1C1SLC18A3SIGMAR1CYP2D6
SCHEMBL41763 0.74
SCHEMBL11796963 0.73 MAOB (0.52) CYP2D6CYP2C19KMT2ALMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11214750-B2 Combinations of phosphorous-containing compounds for use as anti-wear additives in lubricant compositions AFTON CHEMICAL CORPORATION (US) 2022-01-04 US claimed
US-20180002631-A1 Combinations of Phosphorous-Containing Compounds for Use as Anti-Wear Additives in Lubricant Compositions AFTON CHEMICAL CORP (US) 2018-01-04 US claimed
CN-101993758-B Combinations of phosphorus-containing compounds for use as anti-wear additives in lubricant compositions AFTON CHEMICAL CORP 2014-04-02 CN claimed
US-20120184472-A1 COMBINATIONS OF PHOSPHORUS-CONTAINING COMPOUNDS FOR USE AS ANTI-WEAR ADDITIVES IN LUBRICANT COMPOSITION AFTON CHEMICAL CORPORATION (US) 2012-07-19 US claimed
EP-2298854-A1 Combinations of phosphorus-containing compounds for use as anti-wear additives in lubricant compositions Afton Chemical Corporation (US) 2011-03-23 EP claimed
US-20110046029-A1 Combinations of Phosphorus-Containing Compounds For Use As Anti-Wear Additives In Lubricant Compositions AFTON CHEMICAL CORPORATION 2011-02-24 US claimed
CN-117166182-A Heating method of quartz glass cloth and manufacturing method of quartz glass cloth 信越化学工业株式会社 2023-12-05 CN disclosed
US-20220194913-A1 ALICYCLIC EPOXY COMPOUND PRODUCT DAICEL CORPORATION (JP) 2022-06-23 US disclosed
US-11214750-B2 Combinations of phosphorous-containing compounds for use as anti-wear additives in lubricant compositions AFTON CHEMICAL CORPORATION (US) 2022-01-04 US disclosed
US-20180002631-A1 Combinations of Phosphorous-Containing Compounds for Use as Anti-Wear Additives in Lubricant Compositions AFTON CHEMICAL CORP (US) 2018-01-04 US disclosed
CN-101993758-B Combinations of phosphorus-containing compounds for use as anti-wear additives in lubricant compositions AFTON CHEMICAL CORP 2014-04-02 CN disclosed
US-20120184472-A1 COMBINATIONS OF PHOSPHORUS-CONTAINING COMPOUNDS FOR USE AS ANTI-WEAR ADDITIVES IN LUBRICANT COMPOSITION AFTON CHEMICAL CORPORATION (US) 2012-07-19 US disclosed
EP-2298854-A1 Combinations of phosphorus-containing compounds for use as anti-wear additives in lubricant compositions Afton Chemical Corporation (US) 2011-03-23 EP disclosed
EP-0874884-A1 LUBRICANTS WITH IMPROVED RUST INHIBITION EXXON CHEMICAL PATENTS, INC. (US) 1998-11-04 EP disclosed
EP-0873384-A1 POWER TRANSMITTING FLUIDS WITH IMPROVED SHIFT DURABILITY EXXON CHEMICAL PATENTS INC. (US) 1998-10-28 EP disclosed
EP-0856041-A1 POWER TRANSMITTING FLUIDS OF IMPROVED ANTIWEAR PERFORMANCE EXXON CHEMICAL PATENTS INC. (US) 1998-08-05 EP disclosed
WO-1997014771-A1 POWER TRANSMITTING FLUIDS WITH IMPROVED SHIFT DURABILITY EXXON CHEMICAL PATENTS INC. (US) 1997-04-24 WO disclosed
WO-1997014770-A1 POWER TRANSMITTING FLUIDS OF IMPROVED ANTIWEAR PERFORMANCE EXXON CHEMICAL PATENTS INC. (US) 1997-04-24 WO disclosed
WO-1997012949-A1 LUBRICANTS WITH IMPROVED RUST INHIBITION EXXON CHEMICAL PATENTS INC. (US) 1997-04-10 WO disclosed
US-3974224-A HYDROGEN PEROXIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220194913-A1 ALICYCLIC EPOXY COMPOUND PRODUCT OLA1, SEM1, PSMC5 AKR1C3 460/4885AKR1C1 69/4885SLC18A3 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.