Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | CPA2 | P48052 | 1/20 | 0.53 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2735966 | 0.88 | ACE (0.52) | CPA1MMP9MMP8CTSSCTSK | |
| SCHEMBL24558027 | 0.87 | GRIA1 (0.53) | GRIA1CPA1CPA2CPA4MMP9 | |
| SCHEMBL9292479 | 0.87 | CPA1 (0.55) | GRIA1CPA1CPA2CPA4MMP9 | |
| SCHEMBL9334753 | 0.87 | CPA1 (0.55) | GRIA1CPA1CPA2CPA4MMP9 | |
| SCHEMBL8903262 | 0.86 | ACE (0.61) | GRIA1CPA1CPA2CPA4FOLH1 | |
| SCHEMBL30493638 | 0.86 | GRIA1 (0.55) | GRIA1CPA1CPA2CPA4MMP9 | |
| SCHEMBL30493613 | 0.86 | GRIA1 (0.55) | GRIA1CPA1CPA2CPA4MMP9 | |
| SCHEMBL24724924 | 0.86 | GRIA1 (0.57) | GRIA1CPA1CPA2CPA4MMP9 | |
| SCHEMBL12632559 | 0.86 | GRIA1 (0.57) | GRIA1CPA1CPA2CPA4MMP9 | |
| SCHEMBL25139820 | 0.86 | GRIA1 (0.57) | GRIA1CPA1CPA2CPA4MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136807-A1 | Bicyclic compositions and methods for modulating a kinase cascade | KINEX PHARMACEUTICALS, LLC (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136807-A1 | Bicyclic compositions and methods for modulating a kinase cascade | MAP3K20, MAP3K6, MAP3K2 | GRIA1 1993/4885CPA1 4356/4885CPA2 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.