Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 7/20 | 0.54 |
| ▸ | MMP9 | P14780 | 3/20 | 0.54 |
| ▸ | MMP8 | P22894 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | CPA2 | P48052 | 1/20 | 0.48 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | FCER2 | P06734 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25139820 | 1.00 | GRIA1 (0.57) | GRIA1MMP1MMP9MMP8MMP2 | |
| SCHEMBL12632559 | 1.00 | GRIA1 (0.57) | GRIA1MMP1MMP9MMP8MMP2 | |
| SCHEMBL16116808 | 0.89 | GRIA1 (0.56) | GRIA1MMP9MMP8CTSSCTSK | |
| SCHEMBL6862498 | 0.87 | GRIA1 (0.57) | GRIA1MMP1MMP9MMP8MMP2 | |
| SCHEMBL13919555 | 0.87 | MMP1 (0.54) | MMP1MMP9MMP8MMP2MMP3 | |
| SCHEMBL8581074 | 0.86 | GRIA1 (0.60) | GRIA1CTSSCTSKCPA1CPA2 | |
| SCHEMBL25139715 | 0.86 | MMP1 (0.57) | MMP1MMP9MMP8MMP2MMP3 | |
| SCHEMBL11522409 | 0.86 | GRIA1 (0.60) | GRIA1CTSSCTSKCPA1CPA2 | |
| SCHEMBL8671866 | 0.86 | GRIA1 (0.60) | GRIA1CTSSCTSKCPA1CPA2 | |
| SCHEMBL12641900 | 0.86 | GRIA1 (0.56) | GRIA1MMP9MMP8CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |