Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.80 |
| ▸ | ANPEP | P15144 | 5/20 | 0.55 |
| ▸ | PPIG | Q13427 | 2/20 | 0.54 |
| ▸ | PPIB | P23284 | 1/20 | 0.54 |
| ▸ | PPIA | P62937 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040765 | 0.89 | PPID (1.00) | PPIDANPEPPPIGPPIBPPIA | |
| SCHEMBL12643638 | 0.81 | PPID (0.57) | PPIDANPEPPPIGPPIBPPIA | |
| SCHEMBL2034626 | 0.79 | PPID (0.73) | PPIDANPEPPPIGPPIBPPIA | |
| SCHEMBL2039871 | 0.74 | PPID (1.00) | PPIDANPEPPPIGPPIBPPIA | |
| SCHEMBL12643652 | 0.73 | PPID (0.69) | PPIDANPEPPPIGPPIBPPIA | |
| SCHEMBL16270312 | 0.73 | PPID (0.69) | PPIDANPEPPPIGPPIBPPIA | |
| SCHEMBL12643966 | 0.72 | PPID (0.68) | PPIDANPEPPPIGPPIBPPIA | |
| SCHEMBL12643632 | 0.72 | PPID (0.68) | PPIDANPEPPPIGPPIBPPIA | |
| SCHEMBL15832185 | 0.72 | PPID (0.65) | PPIDANPEPPPIGPPIBPPIA | |
| SCHEMBL2035741 | 0.71 | PPID (0.64) | PPIDANPEPPPIGPPIBPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |