Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AOC1 | P19801 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555073 | 0.81 | NAMPT (0.48) | GSK3BMAPTNAMPTATRSIRT3 | |
| SCHEMBL12955312 | 0.80 | KDM4C (0.55) | KDM4C | |
| SCHEMBL24834528 | 0.75 | SIRT3 (0.46) | GSK3BMAPTGSK3APTGS1PTGS2 | |
| SCHEMBL7484295 | 0.75 | NAMPT (0.43) | NAMPTATRALDH1A1CYP17A1RAB9A | |
| SCHEMBL13475708 | 0.72 | TSHR (0.49) | GSK3BMAPTGSK3AATRSMN1; SMN2 | |
| SCHEMBL13475948 | 0.71 | NPC1 (0.46) | GSK3BMAPTGSK3APTGS1PTGS2 | |
| SCHEMBL25890385 | 0.71 | CYP11B1 (0.39) | GSK3BMAPTGSK3ANAMPTCYP17A1 | |
| SCHEMBL30600744 | 0.71 | KDM4C (0.50) | GSK3BMAPTGSK3AATRKMT2A | |
| SCHEMBL2033252 | 0.71 | KDM4C (0.50) | GSK3BMAPTGSK3AATRKMT2A | |
| SCHEMBL692100 | 0.70 | HPGD (0.49) | GSK3BMAPTGSK3AATRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076419-A1 | IMIDAZOPYRIDINE DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2011-06-30 | — | — | WO | disclosed |