SCHEMBL25890385

SCHEMBL25890385

Cc1ccncc1NC(=O)C1(NC(=O)OC(C)(C)C)CC1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
GHSR Q92847 1/20 0.39
CYP17A1 P05093 2/20 0.39
NAMPT P43490 2/20 0.37
BRS3 P32247 1/20 0.37
MAPT P10636 1/20 0.37
GSK3B P49841 1/20 0.37
GSK3A P49840 2/20 0.37
RAB9A P51151 1/20 0.36
KIT P10721 2/20 0.36
MAP4K1 Q92918 1/20 0.35
BDKRB1 P46663 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142826 0.88 GHSR (0.39) GHSRCYP17A1NAMPTBRS3MAPT
SCHEMBL146430 0.86 GHSR (0.41) GHSRCYP17A1NAMPTBRS3RAB9A
SCHEMBL8346749 0.84 GHSR (0.47) GHSRRAB9A
SCHEMBL555073 0.82 NAMPT (0.48) CYP17A1NAMPTMAPTGSK3BRAB9A
SCHEMBL8344329 0.81 KMT2A (0.50) GHSRRAB9A
SCHEMBL31611248 0.80 NAMPT (0.57) GHSRNAMPTRAB9A
SCHEMBL26318454 0.80 NAMPT (0.57) GHSRNAMPTRAB9A
SCHEMBL8345080 0.80 MEN1 (0.52) GHSR
SCHEMBL7484295 0.75 NAMPT (0.43) CYP17A1NAMPTRAB9AMAP4K1
SCHEMBL31654157 0.75 FPR2 (0.54) GHSRNAMPTBDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A CYP11B1 968/4885CYP11B2 1038/4885GHSR 608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.