Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 3/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | PPID | Q08752 | 5/20 | 0.55 |
| ▸ | PPIG | Q13427 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | PPIA | P62937 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14576864 | 0.96 | PPIB (0.63) | PPIBEPHX1PPIDPPIGEPHX2 | |
| SCHEMBL12643850 | 0.92 | EPHX1 (0.66) | PPIBEPHX1PPIDPPIGEPHX2 | |
| SCHEMBL12643755 | 0.86 | SMN1; SMN2 (0.68) | PPIBEPHX1PPIDPPIGEPHX2 | |
| SCHEMBL14576313 | 0.83 | PPIB (0.56) | PPIBPPIDPPIGPPIASMN1; SMN2 | |
| SCHEMBL14617667 | 0.81 | SMN1; SMN2 (0.81) | EPHX1PPIDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL12643760 | 0.80 | PPID (0.63) | PPIBEPHX1PPIDPPIGEPHX2 | |
| SCHEMBL15939528 | 0.79 | PPID (0.65) | PPIBEPHX1PPIDPPIGEPHX2 | |
| SCHEMBL14575947 | 0.79 | PPIB (0.68) | PPIBEPHX1PPIDPPIGEPHX2 | |
| SCHEMBL6962953 | 0.79 | ALDH1A1 (0.73) | KMT2AALDH1A1L3MBTL1TRPV1LMNA | |
| Hydrochloric Acid SCHEMBL6966911 | 0.78 | TRPV1 (0.74) | MAOBKMT2AALDH1A1L3MBTL1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |