Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 4/20 | 0.58 |
| ▸ | NR2E1 | Q9Y466 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SCN1A | P35498 | 2/20 | 0.53 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12649702 | 0.85 | MRGPRX4 (0.57) | HTR1BALDH1A1SLC6A4SMN1; SMN2LMNA | |
| SCHEMBL12649548 | 0.83 | SLC2A1 (0.64) | SLC2A1ALDH1A1SMN1; SMN2LMNAHTR1A | |
| SCHEMBL12649547 | 0.82 | HTR1B (0.57) | HTR1BALDH1A1SLC6A4SMN1; SMN2LMNA | |
| SCHEMBL25689411 | 0.79 | MRGPRX4 (0.57) | HTR1BNR2E1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL27889549 | 0.78 | MRGPRX4 (0.56) | HTR1BNR2E1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL1774820 | 0.77 | MRGPRX4 (0.61) | HTR1BALDH1A1SMN1; SMN2LMNAMRGPRX4 | |
| SCHEMBL25690631 | 0.77 | MRGPRX4 (0.61) | HTR1BALDH1A1HTR6SMN1; SMN2LMNA | |
| SCHEMBL12600506 | 0.77 | MRGPRX4 (0.61) | HTR1BNR2E1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12600468 | 0.76 | MRGPRX4 (0.57) | HTR1BALDH1A1SMN1; SMN2LMNAMRGPRX4 | |
| SCHEMBL29568609 | 0.76 | MRGPRX4 (0.67) | HTR1BALDH1A1SMN1; SMN2LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499112-B1 | SUBSTITUTED 3-(PHENOXYMETHYL) BENZYL AMINES AND PERSONAL CARE COMPOSITIONS | UNILEVER PLC NO 41424 (GB) | 2013-10-16 | — | — | EP | disclosed |
| US-8425885-B2 | Substituted 3-(phenoxymethyl) benzyl amines and personal care compositions | CONOPCO, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20110110871-A1 | SUBSTITUTED 3-(PHENOXYMETHYL) BENZYL AMINES AND PERSONAL CARE COMPOSITIONS | CONOPCO, INC., D/B/A UNILEVER (US) | 2011-05-12 | — | — | US | disclosed |
| WO-2011054805-A1 | SUBSTITUTED 3-(PHENOXYMETHYL) BENZYL AMINES AND PERSONAL CARE COMPOSITIONS | UNILEVER PLC (GB) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110110871-A1 | SUBSTITUTED 3-(PHENOXYMETHYL) BENZYL AMINES AND PERSONAL CARE COMPOSITIONS | TYR, CUTA, BRD3 | SLC2A1 4684/4885HTR1B 836/4885NR2E1 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.