Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.63 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.63 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.54 |
| ▸ | CA1 | P00915 | 6/20 | 0.54 |
| ▸ | CA2 | P00918 | 6/20 | 0.54 |
| ▸ | CA4 | P22748 | 6/20 | 0.54 |
| ▸ | CA5A | P35218 | 6/20 | 0.54 |
| ▸ | CA7 | P43166 | 6/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.54 |
| ▸ | CA6 | P23280 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651482 | 1.00 | P4HB (0.63) | P4HBPDIA4PDIA3TSHRCA12 | |
| SCHEMBL12651802 | 0.96 | P4HB (0.59) | P4HBPDIA4PDIA3TSHRCA12 | |
| SCHEMBL12651652 | 0.96 | P4HB (0.59) | P4HBPDIA4PDIA3TSHRCA12 | |
| SCHEMBL20633976 | 0.92 | P4HB (0.61) | P4HBPDIA4PDIA3TSHRCA12 | |
| SCHEMBL1726710 | 0.91 | P4HB (0.61) | P4HBPDIA4PDIA3TSHRCA12 | |
| SCHEMBL8654501 | 0.91 | P4HB (0.61) | P4HBPDIA4PDIA3TSHRCA12 | |
| SCHEMBL13587888 | 0.91 | P4HB (0.53) | P4HBPDIA4PDIA3TSHRCA12 | |
| SCHEMBL13324379 | 0.91 | P4HB (0.59) | P4HBPDIA4PDIA3TSHRCA12 | |
| SCHEMBL12610466 | 0.89 | P4HB (0.53) | P4HBPDIA4PDIA3TSHRCA12 | |
| SCHEMBL12610600 | 0.89 | P4HB (0.53) | P4HBPDIA4PDIA3TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9707417-B2 | Use of benzotropolone derivatives as UV absorbers and antioxidants and their use in sunscreens and/or cosmetic compositions | BASF SE (DE) | 2017-07-18 | — | — | US | disclosed |
| EP-2296760-B1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2016-03-16 | — | — | EP | disclosed |
| US-20110123468-A1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110123468-A1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | CBR3, SCO2, CBR1 | P4HB 1270/4885PDIA4 1279/4885PDIA3 944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.