Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 11/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.51 |
| ▸ | PTGFR | P43088 | 2/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | PTGIR | P43119 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126529 | 1.00 | MGLL (0.52) | MGLLPTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL126531 | 1.00 | MGLL (0.52) | MGLLPTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL127622 | 0.88 | PTGER3 (0.63) | MGLLPTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL127621 | 0.88 | PTGER3 (0.63) | MGLLPTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL127623 | 0.88 | PTGER3 (0.63) | MGLLPTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL129363 | 0.87 | MGLL (0.57) | MGLLPTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL129364 | 0.87 | MGLL (0.57) | MGLLPTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL129365 | 0.87 | MGLL (0.57) | MGLLPTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL124113 | 0.86 | PTGER4 (0.64) | MGLLPTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL125666 | 0.86 | PTGER4 (0.64) | MGLLPTGER4PTGER3PTGFRPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390036-B1 | PROSTANOIC ACID DERIVATIVES AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN INC (US) | 2012-03-07 | — | — | EP | claimed |