Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.54 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12363946 | 1.00 | TRPV1 (0.54) | TRPV1F9TRPA1TRPM8AKR1C3 | |
| SCHEMBL12653026 | 0.83 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL12653116 | 0.83 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL12652905 | 0.81 | TRPV1 (0.59) | TRPV1DGAT1KCNH2 | |
| SCHEMBL2241285 | 0.78 | TRPV1 (0.85) | TRPV1TRPA1TRPM8 | |
| SCHEMBL4514053 | 0.76 | TRPV1 (0.62) | TRPV1 | |
| Mavatrep SCHEMBL1797450 | 0.76 | TRPV1 (0.85) | TRPV1 | |
| Mavatrep SCHEMBL1796599 | 0.76 | TRPV1 (0.85) | TRPV1 | |
| Mavatrep SCHEMBL29636978 | 0.76 | TRPV1 (0.85) | TRPV1 | |
| SCHEMBL1798882 | 0.76 | TRPV1 (0.85) | TRPV1TRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951829-B2 | Benzimidazole modulators of VR1 | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-31 | — | — | US | disclosed |