Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12653026 | 1.00 | TRPV1 (0.54) | TRPV1POLBALOX5APFEN1SCN9A | |
| SCHEMBL4520138 | 0.85 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL12363946 | 0.83 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL12653025 | 0.83 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL4526680 | 0.82 | TRPV1 (0.51) | TRPV1POLB | |
| SCHEMBL12359213 | 0.80 | TRPV1 (0.60) | TRPV1 | |
| SCHEMBL2239628 | 0.77 | TRPV1 (0.85) | TRPV1SCN9A | |
| SCHEMBL4523218 | 0.77 | TRPV1 (0.64) | TRPV1POLBALOX5APFEN1 | |
| SCHEMBL4533243 | 0.77 | TRPV1 (0.64) | TRPV1POLBALOX5APFEN1 | |
| SCHEMBL4530055 | 0.76 | TRPV1 (0.58) | TRPV1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951829-B2 | Benzimidazole modulators of VR1 | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-31 | — | — | US | disclosed |