⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391822 | 1.00 | CES2 (0.45) | — | |
| SCHEMBL21391917 | 0.97 | CES2 (0.43) | — | |
| SCHEMBL21391916 | 0.97 | CES2 (0.50) | — | |
| SCHEMBL14273180 | 0.97 | CES2 (0.50) | — | |
| SCHEMBL21391824 | 0.94 | CES2 (0.55) | — | |
| SCHEMBL101983 | 0.93 | — | — | |
| SCHEMBL13397790 | 0.93 | — | — | |
| SCHEMBL1420 | 0.90 | — | — | |
| SCHEMBL9010935 | 0.90 | CES2 (0.58) | — | |
| Hydrochloric Acid SCHEMBL22683575 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2983 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899184-A | Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2025-04-29 | — | — | CN | claimed |
| CN-119505238-A | Polyamide-imide resin, polyamide-imide resin film, window, display substrate, and flexible display device | 中化学科学技术研究有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | claimed |
| CN-116410106-B | Benzamide HBV capsid protein inhibitor and preparation method and application thereof | 山东第二医科大学 | 2024-12-06 | — | — | CN | claimed |
| CN-118955467-A | 1, 3-Dithiane substituted conjugated diene compound and preparation method thereof | 兰州大学 | 2024-11-15 | — | — | CN | claimed |
| CN-114685394-B | Phenoxazine derivative based on amide bond, and preparation method and application thereof | 山西大学 | 2024-03-12 | — | — | CN | claimed |
| CN-112174870-B | Preparation method and medicinal application of (R) -1-alkanoyl-2-substituted pyrrolidine-2-carboxamide | 蔡霈 | 2023-07-21 | — | — | CN | claimed |
| CN-116410106-A | Benzamide HBV capsid protein inhibitor and preparation method and application thereof | 潍坊医学院 | 2023-07-11 | — | — | CN | claimed |
| CN-115232126-B | Beta-carbolin-1, 2, 3-triazole compound, preparation method thereof and application of compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2023-04-25 | — | — | CN | claimed |
| CN-115819455-A | Acyl phosphine oxide compound and preparation method thereof | 南方科技大学 | 2023-03-21 | — | — | CN | claimed |
| CN-113367142-A | Composition containing pyridalyl and benzoylurea | 合肥巨卓农业技术开发有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-112174870-A | Preparation method and medicinal application of (R) -1-alkanoyl-2-substituted pyrrolidine-2-formamide | 蔡霈 | 2021-01-05 | — | — | CN | claimed |
| CN-112047917-A | Xanthohumol derivative and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2020-12-08 | — | — | CN | claimed |
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | claimed |
| EP-1506176-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2013-04-24 | — | — | EP | claimed |
| WO-2010115869-A1 | PROPOFOL PHOSPHONYL DERIVATIVES, SYNTHESIS, AND USE IN LONG ACTING FORMULATIONS | SEPS PHARMA N.V. (BE) | 2010-10-14 | — | — | WO | claimed |
| US-20080064876-A1 | Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione | CELGENE CORPORATION | 2008-03-13 | — | — | US | claimed |
| WO-2007136640-A2 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLE-1,3-DIONE | CELGENE CORPORATION (US) | 2007-11-29 | — | — | WO | claimed |
| US-4613668-A | Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1986-09-23 | — | — | US | claimed |
| EP-0155424-A1 | A total synthesis of morphinan compounds by cyclization of cycloalkylcarbonyl compounds | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1985-09-25 | — | — | EP | claimed |