Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12653859 | 1.00 | POLB (0.48) | POLBGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL30685930 | 0.91 | GAA (0.48) | POLBGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL12654125 | 0.88 | GAA (0.44) | POLBGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL29716145 | 0.88 | GAA (0.48) | POLBGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL20625250 | 0.86 | GAA (0.51) | POLBGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL13537902 | 0.85 | BCL9 (0.45) | POLBGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL21498615 | 0.85 | POLB (0.69) | POLBGAACYP1A2CYP2D6 | |
| SCHEMBL2803614 | 0.84 | CYP1A2 (0.49) | POLBGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL2722317 | 0.84 | CYP1A2 (0.49) | POLBGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL1806120 | 0.83 | GAA (0.43) | POLBGAAHTR2ABCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118330-A1 | HIV PROTEASE INHIBITORS AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118330-A1 | HIV PROTEASE INHIBITORS AND METHODS FOR USING | SERPINB1, PREP, PEPD | POLB 496/4885GAA 89/4885HTR2A 4487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.