Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.80 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.67 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.67 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.67 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.67 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.67 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.67 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839085 | 0.89 | FAAH (0.91) | FAAHCA12CA2CA9MAPT | |
| SCHEMBL3606934 | 0.89 | FAAH (1.00) | FAAHMAPT | |
| SCHEMBL12655875 | 0.86 | FAAH (0.79) | FAAHCA12CA2CA9MAPT | |
| SCHEMBL12655878 | 0.85 | FAAH (0.78) | FAAHCA12CA2CA9MAPT | |
| SCHEMBL13545510 | 0.84 | FAAH (1.00) | FAAHMAPTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL3592114 | 0.83 | CA12 (0.90) | FAAHCA12CA2CA9MAPT | |
| SCHEMBL12655542 | 0.83 | CA12 (1.00) | FAAHCA12CA2CA9MAPT | |
| SCHEMBL28869329 | 0.83 | MAPT (1.00) | FAAHCA12CA2CA9MAPT | |
| SCHEMBL20236190 | 0.82 | MAPT (0.80) | FAAHMAPTPOLBSMN1; SMN2 | |
| SCHEMBL12655537 | 0.81 | FAAH (0.80) | FAAHCA12CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060396-A1 | ALIPHATIC AMINES BASED HETEROCYCLES USEFUL AS HIV ENTRY BLOCKERS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |