Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12655486 | 0.83 | NPC1 (0.41) | ALDH1A1HSD17B10TSHRLMNANPSR1 | |
| SCHEMBL17948098 | 0.75 | HSD17B10 (0.44) | ALDH1A1HSD17B10TSHRLMNANPSR1 | |
| SCHEMBL28943307 | 0.75 | HSD17B10 (0.51) | ALDH1A1HSD17B10LMNANPSR1NPC1 | |
| SCHEMBL3940084 | 0.75 | NPC1 (0.48) | ALDH1A1HSD17B10TSHRLMNANPSR1 | |
| SCHEMBL9078128 | 0.75 | HSD17B10 (0.48) | ALDH1A1HSD17B10LMNANPSR1NPC1 | |
| SCHEMBL4244079 | 0.72 | HSD17B10 (0.50) | ALDH1A1HSD17B10LMNANPSR1NPC1 | |
| SCHEMBL2684345 | 0.72 | HSD17B10 (0.50) | ALDH1A1HSD17B10LMNANPSR1NPC1 | |
| SCHEMBL28232406 | 0.71 | HSD17B10 (0.47) | ALDH1A1HSD17B10LMNANPSR1NPC1 | |
| SCHEMBL12647717 | 0.71 | HSD17B10 (0.40) | ALDH1A1HSD17B10TSHRLMNANPSR1 | |
| SCHEMBL1319725 | 0.70 | EPHX1 (0.47) | ALDH1A1HSD17B10LMNANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060000-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |