Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28943307 | 0.87 | HSD17B10 (0.51) | NPC1HSD17B10EPHX1SMN1; SMN2LMNA | |
| SCHEMBL9078128 | 0.87 | HSD17B10 (0.48) | NPC1HSD17B10EPHX1SMN1; SMN2LMNA | |
| SCHEMBL2684345 | 0.83 | HSD17B10 (0.50) | NPC1HSD17B10EPHX1SMN1; SMN2LMNA | |
| SCHEMBL4244079 | 0.83 | HSD17B10 (0.50) | NPC1HSD17B10EPHX1SMN1; SMN2LMNA | |
| SCHEMBL29571557 | 0.83 | SMN1; SMN2 (0.45) | NPC1HSD17B10EPHX1SMN1; SMN2LMNA | |
| SCHEMBL1319725 | 0.81 | EPHX1 (0.47) | NPC1HSD17B10EPHX1SMN1; SMN2LMNA | |
| SCHEMBL27982366 | 0.81 | HSD17B10 (0.48) | NPC1HSD17B10EPHX1SMN1; SMN2LMNA | |
| SCHEMBL27982374 | 0.81 | HSD17B10 (0.48) | NPC1HSD17B10EPHX1SMN1; SMN2LMNA | |
| SCHEMBL30438366 | 0.80 | EPHX1 (0.46) | NPC1HSD17B10EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28232406 | 0.79 | HSD17B10 (0.47) | NPC1HSD17B10EPHX1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |