Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.43 |
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA9 | Q16790 | 11/20 | 0.43 |
| ▸ | CA4 | P22748 | 7/20 | 0.43 |
| ▸ | CA7 | P43166 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595797 | 0.92 | CA1 (0.50) | CA1CA2CA9CA4CA7 | |
| SCHEMBL12656424 | 0.91 | CA1 (0.43) | CA1CA2CA9CA4CA7 | |
| SCHEMBL12656535 | 0.90 | CA1 (0.46) | CA1CA2CA9CA4CA7 | |
| SCHEMBL12656460 | 0.90 | CA1 (0.43) | CA1CA2CA9CA4CA7 | |
| SCHEMBL12656464 | 0.88 | CA1 (0.46) | CA1CA2CA9CA4CA7 | |
| SCHEMBL12656272 | 0.87 | CA1 (0.48) | CA1CA2CA9CA4CA7 | |
| SCHEMBL12656127 | 0.86 | CA1 (0.41) | CA1CA2CA9CA4CA7 | |
| SCHEMBL12656427 | 0.86 | CA1 (0.51) | CA1CA2CA9CA4CA7 | |
| SCHEMBL12656534 | 0.84 | CA1 (0.43) | CA1CA2CA9CA4CA7 | |
| SCHEMBL12656533 | 0.84 | CA1 (0.43) | CA1CA2CA9CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011063293-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIHELMINTH AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-26 | — | — | WO | disclosed |