⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15694887 | 0.79 | SOS1 (0.34) | — | |
| SCHEMBL20019806 | 0.79 | SOS1 (0.34) | — | |
| SCHEMBL12626725 | 0.75 | — | — | |
| SCHEMBL12656471 | 0.69 | TSHR (0.33) | — | |
| SCHEMBL12656406 | 0.68 | SIGMAR1 (0.30) | — | |
| SCHEMBL12656407 | 0.68 | — | — | |
| SCHEMBL15141887 | 0.62 | — | — | |
| SCHEMBL20019683 | 0.61 | — | — | |
| SCHEMBL15478468 | 0.61 | SOS1 (0.30) | — | |
| SCHEMBL20758383 | 0.61 | SOS1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105481-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |