Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22275912 | 0.80 | CHRNB2 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL7697474 | 0.79 | HPGD (0.45) | HPGDCTBP2L3MBTL1NPC1RAB9A | |
| SCHEMBL13849277 | 0.78 | HPGD (0.42) | HPGDCTBP2FAAHALDH1A1MGLL | |
| SCHEMBL7517689 | 0.77 | HPGD (0.50) | HPGDCTBP2L3MBTL1NPC1RAB9A | |
| SCHEMBL18772414 | 0.74 | HPGD (0.46) | HPGDCTBP2FAAHALDH1A1MGLL | |
| SCHEMBL24718312 | 0.73 | HPGD (0.43) | HPGDALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL14298318 | 0.73 | SMN1; SMN2 (0.45) | HPGDALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL19289931 | 0.72 | SLC5A2 (0.34) | SMN1; SMN2 | |
| SCHEMBL27053828 | 0.72 | HPGD (0.49) | HPGDCTBP2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL20618816 | 0.70 | IDO1 (0.44) | HPGDCTBP2FAAHALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163262-B1 | PHENYLALANINE DERIVATIVES | US GOV HEALTH & HUMAN SERV (US) | 2011-05-11 | — | — | EP | disclosed |