SCHEMBL12657232

SCHEMBL12657232

CC[n+]1ccccc1/C(C)=C/c1ccc(N)cc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
GFER P55789 1/20 0.41
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
STAT3 P40763 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP19A1 P11511 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14194574 0.85 KMT2A (0.37) NPC1RAB9AMEN1ALDH1A1MAPT
SCHEMBL10104055 0.77 KDM4E (0.32) NPC1RAB9AMEN1ALDH1A1MAPT
SCHEMBL12657103 0.71 RAB9A (0.67) NPC1RAB9AGFERMEN1ALDH1A1
SCHEMBL12657269 0.71 ESR1 (0.44) NPC1RAB9AGFERCYP19A1MAOA
SCHEMBL12657235 0.70 APP (0.33) CYP2D6CYP2C19
SCHEMBL17911707 0.69 MEN1 (0.40) NPC1RAB9AMEN1ALDH1A1MAPT
SCHEMBL14393482 0.69 KMT2A (0.43) NPC1RAB9AGFERMEN1ALDH1A1
SCHEMBL8939242 0.69 ESR1 (0.53) NPC1RAB9AGFERALDH1A1MAPT
SCHEMBL19582788 0.69 CYP2D6 (0.41) NPC1RAB9AMEN1ALDH1A1MAPT
SCHEMBL1724143 0.69 CYP2D6 (0.41) NPC1RAB9AMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140110676-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-04-24 US disclosed
EP-2004756-B1 DYEING COMPOSITION COMPRISING A THIOL/DISULPHIDE FLUORESCENT COLORANT HAVING AN EXTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT OREAL (FR) 2011-05-04 EP disclosed