Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.59 |
| ▸ | CHAT | P28329 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MAT2A | P31153 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680312 | 0.84 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL30612471 | 0.84 | CHAT (0.76) | CHATALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL9678907 | 0.84 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL19003408 | 0.84 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL900823 | 0.84 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL12519753 | 0.82 | CHAT (0.80) | CHATALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL10001242 | 0.82 | CHAT (0.80) | CHATALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL10257279 | 0.79 | — | — | |
| SCHEMBL12657463 | 0.79 | CHAT (0.52) | CHATALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL12657083 | 0.79 | APP (0.53) | APPRAB9AKCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004756-B1 | DYEING COMPOSITION COMPRISING A THIOL/DISULPHIDE FLUORESCENT COLORANT HAVING AN EXTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | OREAL (FR) | 2011-05-04 | — | — | EP | disclosed |
| WO-2008034272-A1 | STILBAZOLIUM SALT | ETH Zürich (CH) | 2008-03-27 | — | — | WO | disclosed |
| WO-2007128691-A1 | HIGH CAPACITY OPTICAL STORAGE MEDIA COMPRISING ORGANOMETALLIC ION PAIRS | CIBA HOLDING INC. (CH) | 2007-11-15 | — | — | WO | disclosed |