Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12387901 | 0.86 | MAPT (0.47) | MAPTLMNA | |
| SCHEMBL8533249 | 0.86 | MAPT (0.47) | MAPTLMNA | |
| SCHEMBL12240373 | 0.82 | MAPT (0.42) | MAPTLMNAHDAC8 | |
| SCHEMBL10104065 | 0.80 | ALDH1A1 (0.46) | CHATRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL12657096 | 0.80 | CHAT (0.44) | CHATRAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL30612471 | 0.79 | CHAT (0.76) | CHATRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL12657239 | 0.79 | APP (0.59) | CHATRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL8422585 | 0.79 | LMNA (0.53) | CHATRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL12657253 | 0.78 | CHAT (0.58) | CHATRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL23373806 | 0.77 | ALDH1A1 (0.44) | CHATRAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004756-B1 | DYEING COMPOSITION COMPRISING A THIOL/DISULPHIDE FLUORESCENT COLORANT HAVING AN EXTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | OREAL (FR) | 2011-05-04 | — | — | EP | disclosed |