Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.58 |
| ▸ | FAAH | O00519 | 6/20 | 0.58 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL741572 | 0.85 | MGLL (0.59) | MGLLFAAHDDAH1NPSR1HSP90AA1 | |
| SCHEMBL514697 | 0.85 | MGLL (0.59) | MGLLFAAHDDAH1NPSR1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL28737900 | 0.84 | MGLL (0.58) | MGLLFAAHDDAH1NPSR1HSP90AA1 | |
| SCHEMBL12683541 | 0.84 | MGLL (0.62) | MGLLFAAHDDAH1NPSR1HSP90AA1 | |
| Water SCHEMBL17644778 | 0.84 | MGLL (0.58) | MGLLFAAHDDAH1NPSR1HSP90AA1 | |
| SCHEMBL8090506 | 0.83 | MGLL (0.56) | MGLLFAAHDDAH1NPSR1HSP90AA1 | |
| Hydrazine SCHEMBL27822007 | 0.83 | MGLL (0.56) | MGLLFAAHDDAH1NPSR1HSP90AA1 | |
| SCHEMBL27951835 | 0.82 | MGLL (0.73) | MGLLFAAHDDAH1NPSR1HSP90AA1 | |
| SCHEMBL28264790 | 0.81 | MGLL (0.83) | MGLLFAAHDDAH1NPSR1HSP90AA1 | |
| SCHEMBL24637617 | 0.80 | MGLL (0.57) | MGLLFAAHDDAH1NPSR1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968223-B1 | BIOCONJUGATION OF MACROMOLECULES | SIGMA ALDRICH CO LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| EP-2319855-A1 | Bioconjugation of Macromolecules | Sigma-Aldrich Co. (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2319854-A1 | Bioconjugation Of Macromolecules | Sigma-Aldrich Co. (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2256133-A1 | Bioconjugation of macromolecules | Sigma-Aldrich Co. (US) | 2010-12-01 | — | — | EP | disclosed |