Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 2/20 | 0.67 |
| ▸ | TK1 | P04183 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALB | P02768 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18324639 | 0.91 | TK2 (0.64) | TK2TK1LMNATSHRALB | |
| SCHEMBL24059301 | 0.89 | TK2 (0.68) | TK2TK1LMNATSHRALB | |
| SCHEMBL26661810 | 0.88 | TK2 (0.76) | TK2TK1LMNATSHRALB | |
| SCHEMBL2056538 | 0.86 | TK2 (0.73) | TK2TK1LMNATSHRALB | |
| SCHEMBL2056542 | 0.86 | TK2 (0.73) | TK2TK1LMNATSHRALB | |
| SCHEMBL9484973 | 0.86 | TK2 (0.75) | TK2TK1LMNATSHRALB | |
| SCHEMBL18184309 | 0.85 | TK2 (0.63) | TK2TK1LMNATSHRALB | |
| SCHEMBL11600096 | 0.84 | TK2 (0.71) | TK2TK1LMNATSHRALB | |
| SCHEMBL11600089 | 0.84 | TK2 (0.71) | TK2TK1LMNATSHRALB | |
| 3-Amino- 3-Deoxythymidine SCHEMBL1415407 | 0.84 | TK1 (0.68) | TK2TK1LMNATSHRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2319854-A1 | Bioconjugation Of Macromolecules | Sigma-Aldrich Co. (US) | 2011-05-11 | — | — | EP | disclosed |