Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658115 | 0.90 | NR4A2 (0.45) | NR4A2KDM4EALDH1A1HPGDSLC6A4 | |
| SCHEMBL12658270 | 0.90 | NR4A2 (0.45) | NR4A2ALDH1A1SLC6A4MAPTMEN1 | |
| SCHEMBL12658116 | 0.89 | NR4A2 (0.44) | NR4A2KDM4EALDH1A1HPGDSLC6A4 | |
| SCHEMBL12658026 | 0.84 | NR4A2 (0.48) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| Lynamicin A SCHEMBL12658027 | 0.81 | NR4A2 (0.61) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| SCHEMBL12658207 | 0.81 | NR4A2 (0.45) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| SCHEMBL12658117 | 0.81 | NR4A2 (0.45) | NR4A2KDM4EALDH1A1HPGDSLC6A4 | |
| SCHEMBL12658015 | 0.79 | F7 (0.42) | NR4A2SLC6A4F7F3HTR2A | |
| SCHEMBL12658124 | 0.78 | NR4A2 (0.54) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| Lynamicin B SCHEMBL12658014 | 0.77 | NR4A2 (0.55) | NR4A2KDM4EALDH1A1HPGDPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711486-B1 | BIS-INDOLE PYRROLES USEFUL AS ANTIMICROBIAL AGENTS | NEREUS PHARMACEUTICALS INC (US) | 2011-05-11 | — | — | EP | disclosed |