Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.38 |
| ▸ | TUBB | P07437 | 4/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658115 | 0.91 | NR4A2 (0.45) | NR4A2KDM4EALDH1A1HPGDTUBB4A | |
| SCHEMBL12658016 | 0.90 | SLC6A4 (0.37) | NR4A2KDM4EALDH1A1HPGDSLC6A4 | |
| Lynamicin D SCHEMBL12658118 | 0.83 | NR4A2 (0.63) | NR4A2KDM4EALDH1A1HPGDTUBB4A | |
| SCHEMBL12658015 | 0.81 | F7 (0.42) | NR4A2SLC6A4 | |
| SCHEMBL12658126 | 0.81 | NR4A2 (0.44) | NR4A2KDM4EALDH1A1HPGDTUBB4A | |
| SCHEMBL12658116 | 0.81 | NR4A2 (0.44) | NR4A2KDM4EALDH1A1HPGDTUBB4A | |
| SCHEMBL12658199 | 0.80 | HTR2A (0.38) | KDM4EALDH1A1HPGDSLC6A4MAPT | |
| Lynamicin E SCHEMBL12658018 | 0.78 | NR4A2 (0.56) | NR4A2KDM4EALDH1A1HPGDTUBB4A | |
| SCHEMBL12658026 | 0.77 | NR4A2 (0.48) | NR4A2KDM4EALDH1A1HPGDTUBB4A | |
| SCHEMBL12658120 | 0.77 | NR4A2 (0.55) | NR4A2KDM4EALDH1A1HPGDTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711486-B1 | BIS-INDOLE PYRROLES USEFUL AS ANTIMICROBIAL AGENTS | NEREUS PHARMACEUTICALS INC (US) | 2011-05-11 | — | — | EP | disclosed |