SCHEMBL12658192

SCHEMBL12658192

COC(C)(C)C(C)(C)OBc1cc2cc(B3OC(C)(C)C(C)(C)O3)sc2s1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1830220 0.76 LPL (0.35) USP30
SCHEMBL14854176 0.71 USP30 (0.31) USP30
SCHEMBL12646068 0.67 USP30 (0.33) USP30
SCHEMBL18403177 0.67
SCHEMBL12687329 0.66 CSF1R (0.33)
SCHEMBL16016263 0.65
SCHEMBL13654200 0.64 EGFR (0.31)
SCHEMBL14605416 0.64
SCHEMBL13368160 0.63 USP30 (0.31) USP30
SCHEMBL13721705 0.62 MAPK1 (0.34) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754736-B1 Process for the polymerisation of thiophene or selenophene derivatives MERCK PATENT GMBH (DE) 2011-05-11 EP disclosed