Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944117 | 1.00 | PLG (0.42) | PLGPLATLMNANAAACHRM2 | |
| SCHEMBL12658589 | 1.00 | PLG (0.42) | PLGPLATLMNANAAACHRM2 | |
| SCHEMBL21765657 | 0.89 | NAAA (0.48) | NAAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL2253713 | 0.89 | — | — | |
| SCHEMBL28037534 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL22466294 | 0.87 | — | — | |
| SCHEMBL15305183 | 0.83 | CHRM2 (0.38) | PLGPLATLMNANAAACHRM2 | |
| SCHEMBL15305195 | 0.83 | CHRM2 (0.38) | PLGPLATLMNANAAACHRM2 | |
| SCHEMBL11671947 | 0.82 | NAAA (0.68) | LMNANAAASMN1; SMN2 | |
| SCHEMBL11408733 | 0.82 | NAAA (0.46) | PLGPLATLMNANAAACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044101-B1 | AMINOTHIAZOLE DERIVATIVES AND THEIR USES AS ANTIBACTERIAL AGENTS | NOVARTIS AG (CH) | 2013-10-09 | — | — | EP | disclosed |
| EP-2322536-A2 | Aminothiazole derivatives and their uses as antibacterial agents | Novartis AG (CH) | 2011-05-18 | — | — | EP | disclosed |