SCHEMBL12661880

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12662003	0.90	TRPV1 (0.43)	PARP1SIRT1HDAC3HDAC7HDAC10
	SCHEMBL12661931	0.89	PARP1 (0.41)	PARP1SIRT1HDAC3HDAC7HDAC10
	SCHEMBL12661879	0.88	PARP1 (0.57)	PARP1SIRT1HDAC3HDAC7HDAC10
	SCHEMBL12661885	0.85	PARP1 (0.53)	PARP1SIRT1HDAC3HDAC7HDAC10
	SCHEMBL1895860	0.82	PARP1 (0.54)	PARP1KMT2ANPC1RAB9ATSHR
	SCHEMBL12662004	0.79	PARP1 (0.46)	PARP1HDAC6TRPV1KMT2AMEN1
	SCHEMBL12661934	0.78	PARP1 (0.45)	PARP1SIRT1TRPV1NPC1RAB9A
	SCHEMBL12661886	0.78	PARP1 (0.54)	PARP1HDAC3HDAC7HDAC10HDAC6
	SCHEMBL12662006	0.75	SMN1; SMN2 (0.45)	PARP1HDAC3HDAC6TRPV1KMT2A
	SCHEMBL12661951	0.75	PIM1 (0.42)	PARP1SIRT1PIM1KMT2AGRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.