Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 20/20 | 0.79 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.77 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426189 | 1.00 | SLC5A2 (0.79) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A | |
| SCHEMBL12426037 | 0.88 | SLC5A2 (1.00) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A | |
| SCHEMBL19312345 | 0.87 | SLC5A2 (1.00) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A | |
| Ipragliflozin SCHEMBL11971945 | 0.87 | SLC5A2 (1.00) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A | |
| SCHEMBL12426046 | 0.87 | SLC5A2 (0.79) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A | |
| Ipragliflozin SCHEMBL24037936 | 0.87 | SLC5A2 (1.00) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A | |
| SCHEMBL147932 | 0.87 | SLC5A2 (1.00) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A | |
| Ipragliflozin SCHEMBL23731432 | 0.87 | SLC5A2 (1.00) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A | |
| Ipragliflozin SCHEMBL337645 | 0.87 | SLC5A2 (1.00) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A | |
| SCHEMBL9973937 | 0.87 | SLC5A2 (1.00) | SLC5A2SLC5A1SLC6A3CHRM1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1980560-B1 | C-glycoside derivatives for the treatment of diabetes | ASTELLAS PHARMA INC (JP) | 2011-05-25 | — | — | EP | disclosed |