SCHEMBL1266331

SCHEMBL1266331

CCCCCCCCCCCCCCCCCCc1ccc(Nc2nc(Nc3ccc(CCCCCCCCCCCCCCCCCC)cc3)nc(Nc3ccc(CCCCCCCCCCCCCCCCCC)cc3)n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK17A Q9UEE5 3/20 0.54
STK17B O94768 1/20 0.54
KCNH3 Q9ULD8 2/20 0.54
POLA1 P09884 5/20 0.53
ESR1 P03372 2/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
TACR2 P21452 2/20 0.53
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
SHBG P04278 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSPD1 P10809 1/20 0.53
ADRB3 P13945 1/20 0.53
HTR2C P28335 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1264648 1.00 STK17A (0.54) STK17ASTK17BKCNH3POLA1ESR1
SCHEMBL9296086 0.91 NR1I2 (0.55) STK17ASTK17BKCNH3POLA1KDM4E
SCHEMBL2416578 0.91 LMNA (0.50) STK17ASTK17BKCNH3POLA1ESR1
SCHEMBL28788723 0.91 POLA1 (0.53) STK17ASTK17BKCNH3POLA1HTR2A
SCHEMBL27817598 0.91 POLA1 (0.53) STK17ASTK17BKCNH3POLA1HTR2A
SCHEMBL60027 0.88 ESR1 (0.61) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL2391508 0.88 ESR1 (0.61) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL60134 0.88 ESR1 (0.61) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL284616 0.88 ESR1 (0.61) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL294666 0.88 ESR1 (0.61) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2291562-B1 METHOD OF MAKING ELECTRET ARTICLES BASED ON ZETA POTENTIAL 3M INNOVATIVE PROPERTIES CO (US) 2017-01-04 EP disclosed
EP-2291562-B1 METHOD OF MAKING ELECTRET ARTICLES BASED ON ZETA POTENTIAL 3M INNOVATIVE PROPERTIES CO (US) 2017-01-04 EP disclosed
US-8529671-B2 Electret webs with charge-enhancing additives 3M INNOVATIVE PROPERTIES COMANY (US) 2013-09-10 US disclosed
EP-2222908-B1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES CO (US) 2013-01-16 EP disclosed
EP-2291562-A1 METHOD OF MAKING ELECTRET ARTICLES BASED ON ZETA POTENTIAL 3M Innovative Properties Company (US) 2011-03-09 EP disclosed
US-20110041471-A1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES COMPANY 2011-02-24 US disclosed
EP-2222908-A1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M Innovative Properties Company (US) 2010-09-01 EP disclosed
US-7765698-B2 Method of making electret articles based on zeta potential 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-08-03 US disclosed
US-7765698-B2 Method of making electret articles based on zeta potential 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-08-03 US disclosed
WO-2009148703-A1 METHOD OF MAKING ELECTRET ARTICLES BASED ON ZETA POTENTIAL 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-10 WO disclosed
US-20090293279-A1 METHOD OF MAKING ELECTRET ARTICLES BASED ON ZETA POTENTIAL 3M INNOVATIVE PROPERTIES COMPANY 2009-12-03 US disclosed
US-20090293279-A1 METHOD OF MAKING ELECTRET ARTICLES BASED ON ZETA POTENTIAL 3M INNOVATIVE PROPERTIES COMPANY 2009-12-03 US disclosed
WO-2009076064-A1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-06-18 WO disclosed