Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.51 |
| ▸ | NOS3 | P29474 | 4/20 | 0.48 |
| ▸ | NOS1 | P29475 | 4/20 | 0.48 |
| ▸ | NOS2 | P35228 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPR3 | P17342 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13071694 | 1.00 | TAS1R3 (0.51) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL8299773 | 1.00 | TAS1R3 (0.51) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL10421717 | 0.82 | TAS1R3 (0.50) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL1666836 | 0.82 | TAS1R3 (0.37) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL8294718 | 0.81 | TAS1R3 (0.36) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL10210577 | 0.80 | NPSR1 (0.50) | CYP2C9NPR3CYP2C19POLB | |
| SCHEMBL1992438 | 0.80 | TAS1R3 (0.36) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL12627973 | 0.80 | NPSR1 (0.50) | CYP2C9NPR3CYP2C19POLB | |
| SCHEMBL14609391 | 0.80 | TAS1R3 (0.49) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL8297645 | 0.80 | TAS1R3 (0.49) | TAS1R3TAS1R1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637705-B2 | Amphiphilic oxalamide organogelators designed for gelation of organic solvents, water and hydrocarbon commercial fuels | RUDJER BOSKOVIC INSTITUTE (HR) | 2014-01-28 | — | — | US | disclosed |
| EP-2139910-B1 | METHOD FOR THE SYNTHESIS OF PEPTIDES WITHOUT SOLVENT | CENTRE NAT RECH SCIENT (FR) | 2011-05-25 | — | — | EP | disclosed |
| WO-2008125418-A2 | METHOD FOR THE SYNTHESIS OF PEPTIDES WITHOUT SOLVENT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-10-23 | — | — | WO | disclosed |