Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049063 | 0.86 | AR (0.55) | ARPARP1TNKS2ALDH1A1KMT2A | |
| SCHEMBL12667294 | 0.84 | MAPT (0.51) | ARALDH1A1KMT2AMEN1GAA | |
| SCHEMBL12668929 | 0.82 | ALDH1A1 (0.58) | GPR84ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL12668033 | 0.80 | KDM4E (0.60) | ARGPR84ALDH1A1KMT2AMEN1 | |
| SCHEMBL12667296 | 0.80 | KMT2A (0.44) | ARALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12667304 | 0.79 | HSD17B10 (0.49) | ARGPR84TNKS2ALDH1A1KMT2A | |
| SCHEMBL12649315 | 0.78 | AR (0.58) | ARPARP1TNKS2ALDH1A1KMT2A | |
| SCHEMBL12668935 | 0.78 | ALDH1A1 (0.56) | GPR84ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL12668022 | 0.77 | ALDH1A1 (0.55) | GPR84ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL5145582 | 0.77 | HTR2A (0.54) | KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060036-A1 | BICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |