Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 19/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12669658 | 0.92 | BRAF (0.43) | BRAFNR1I2 | |
| SCHEMBL1869538 | 0.92 | BRAF (0.43) | BRAFNR1I2 | |
| SCHEMBL12669660 | 0.91 | BRAF (0.38) | BRAFNR1I2 | |
| SCHEMBL1873008 | 0.84 | BRAF (0.42) | BRAFNR1I2 | |
| SCHEMBL1870084 | 0.84 | BRAF (0.44) | BRAFNR1I2ADRA1A | |
| SCHEMBL12669102 | 0.84 | BRAF (0.42) | BRAFNR1I2 | |
| SCHEMBL1868804 | 0.83 | RIPK2 (0.41) | BRAF | |
| SCHEMBL12668215 | 0.83 | BRAF (0.45) | BRAFNR1I2 | |
| SCHEMBL12670298 | 0.83 | BRAF (0.50) | BRAFNR1I2 | |
| SCHEMBL12669770 | 0.83 | BRAF (0.44) | BRAFNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011059610-A1 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-05-19 | — | — | WO | disclosed |