Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | TOP1 | P11387 | 4/20 | 0.38 |
| ▸ | CYCS | P99999 | 4/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 2/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863470 | 0.84 | STAT3 (0.59) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL1861247 | 0.82 | STAT1 (0.53) | STAT3STAT1TOP1ENPP2CYP3A4 | |
| SCHEMBL12633142 | 0.81 | STAT3 (0.55) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL4266558 | 0.80 | STAT3 (0.63) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL3557943 | 0.79 | STAT3 (0.68) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL9590030 | 0.78 | STAT3 (0.60) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL8996959 | 0.77 | STAT3 (0.59) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL12448930 | 0.77 | STAT3 (0.56) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL27252011 | 0.77 | TOP1 (0.59) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL8689820 | 0.76 | STAT3 (0.68) | STAT3STAT1TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288528-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti—Società di Esercizio S.p.A. (IT) | 2012-10-16 | — | — | US | disclosed |
| US-7947674-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti (IT) | 2011-05-24 | — | — | US | disclosed |
| US-20110112464-A1 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 2011-05-12 | — | — | US | disclosed |