SCHEMBL12679042

SCHEMBL12679042

C=C(c1ccc(C(=C)c2ccc(N(C)C)cc2)cc1)c1ccc(N(C)C)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.83
KMT2A Q03164 3/20 0.83
ALDH1A1 P00352 8/20 0.58
HPGD P15428 3/20 0.58
MAPT P10636 3/20 0.58
TSHR P16473 4/20 0.58
ALOX15 P16050 4/20 0.58
HSD17B10 Q99714 3/20 0.58
MAPK1 P28482 4/20 0.56
CYP3A4 P08684 3/20 0.56
HBB P68871 1/20 0.56
RAB9A P51151 3/20 0.50
NPC1 O15118 3/20 0.50
GFER P55789 2/20 0.48
HTT P42858 2/20 0.48
GPR55 Q9Y2T6 1/20 0.48
SLC2A1 P11166 1/20 0.46
TDP1 Q9NUW8 3/20 0.46
TP53 P04637 1/20 0.46
POLB P06746 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441802 1.00 MEN1 (0.83) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL607222 0.91 KMT2A (1.00) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL9099853 0.91 MEN1 (0.70) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL9100171 0.89 KMT2A (0.68) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL6342854 0.89 MEN1 (0.68) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL6342371 0.89 MEN1 (0.68) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL17811466 0.87 MEN1 (0.78) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL10692801 0.85 MEN1 (0.63) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL9098425 0.85 MEN1 (0.63) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL10603474 0.85 MEN1 (0.63) MEN1KMT2AALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-20100330475-A1 IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE BEARING MEMBER RICOH COMPANY LIMITED (JP) 2010-12-30 US disclosed